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IGF-1 LR3 operates downstream., It does not stimulate growth hormone release., It is the signal growth hormone eventually produces., IGF-1 LR3 is a modified analog of Insulin-Like Growth Factor-1,

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Recombinant bovine/porcine IGF-1 LR3 protein (Qk114-FG)

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Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice

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