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Each batch is reviewed for peptide integrity, purity levels, and contaminants, with a COA included

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To identify potential targets that enhance the efficacy of CDK4/6 inhibitors and endocrine therapy, we performed whole genome CRISPR/Cas9 suppressor screens, which unexpectedly identified GPX4 depletion as the top hit sensitising palbociclib and giredestrant treated cells, with multiple other genes involved in ferroptosis modulating sensitivity