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Cochrane Database Syst Rev 2014, Issue 3

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How They Work Support hepatic fat metabolism via MIC compounds Deliver nutrients at 100% IM absorption Support liver function and fat export Inositol sensitizes insulin signaling B12 restores metabolic energy foundation Best results as part of a broader protocol What Patients Report Improved energy levels — often from week 1 Reduced afternoon fatigue Improved exercise capacity and recovery Reduced carbohydrate cravings (inositol) More consistent weight management progress Results vary with diet, exercise, and baseline How They Differ GLP-1: appetite suppression + glucose regulation Lipotropic: fat metabolism + liver function Not competitive — different mechanisms Commonly combined for complementary support B12 addresses fatigue GLP-1 patients experience Inform your NP of all current medications Benefits of B12 & Lipotropic Injections