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They are integrated into the membranes by 12 transmembrane regions and contain a STAS domain, found in SULTRs and with a significant similarity to bacterial a nti- s igma factor antagonists (Takahashi et al., 2011a,b)

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The content of the 5-HT metabolite (5-hydroxyindoleacetic acid: 5-HIAA) in the PFC of prenatal VPA mice was lower (Fig