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8 Conclusion Deficiencies in complex B vitamins, particularly vitamins B9 (folate) and B12 (cobalamin), have significant neuropsychiatric manifestations that can profoundly impact mental and neurological health

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Also, an essential point to remember in the cytoprotective effect of agents is capsaicin-sensitive afferent neurons[45,46], which regulate vascular function in many somatic and visceral tissues, including the regulation of local blood flow in the gastrointestinal tract