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Patients with RP show a significant reduction in the GSH/GSSG ratio in the aqueous humor, and a significant increase in protein carbonyl content, suggesting oxidative stress and oxidative damage in the eyes of these patients [195]

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The Role of Microclots in Fatigue Just as the blocking of microcapillaries by microclots gives a ready explanation for POTS, it also gives a ready explanation for fatigue as tissues that rely on aerobic respiration for their normal function are deprived of oxygen